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Sucralfate (Carafate®) for Dogs and Cats

Sucralfate (Carafate®) for Dogs and Cats

Overview of Sucralfate for Dogs and Cats

  • Sucralfate, commonly known by the brand name Carafate®, is used in the treatment and prevention of oral (mouth), esophagus (food tube), stomach and intestinal ulcers in dogs and cats.
  • Stomach ulcers and erosions are relatively common complications of kidney failure, bloat (of the stomach), treatment with steroids, administration of non-steroidal anti-inflammatory drugs (NSAIDs) and primary diseases of the stomach. Frequently, drug therapy is necessary to heal ulcers and prevent further problems.
  • Sucralfate is an anti-ulcer drug useful for the treatment and prevention of gastric (stomach) and intestinal ulcers.
  • The exact way by which sucralfate prevents ulcers is unknown. It is thought, however, that sucralfate reacts with hydrochloric acid in the stomach, forming a paste-like substance that binds to ulcerated areas. This acts to protect the area from other stomach acids, serving as a gastric “Band-Aid.”
  • Sucralfate is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.
  • This drug is not approved for use in animals by the Food and Drug Administration but it is prescribed legally by veterinarians as an extra-label drug.

Brand Names and Other Names of Sucralfate

  • This drug is registered for use in humans only.
  • Human formulations: Carafate® (Hoechst Marion Roussel)
  • Veterinary formulations: None

Uses of Sucralfate for Dogs and Cats

  • Sucralfate is used in the treatment and prevention of oral (mouth), esophagus (food tube), stomach and intestinal ulcers.
  • Sucralfate promotes healing in animals with ulcers or erosions (shallow depressions in the stomach lining).
  • Sucralfate may be useful in preventing gastritis (stomach inflammation) caused by ulcerogenic drugs (such as aspirin).
  • Another use is in the management of acid reflux disease to reduce injury to the esophagus.

Precautions and Side Effects

  • While generally safe and effective when prescribed by a veterinarian, sucralfate can cause side effects in some animals.
  • Sucralfate should not be used in animals with known hypersensitivity or allergy to the drug.
  • Sucralfate may interact with other medications. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with sucralfate. Such drugs include tetracycline, cimetidine and digoxin.
  • Sucralfate can cause mild constipation (usually temporary).

How Sucralfate Is Supplied

  • Sucralfate is available in 1 gram (1,000 mg) scored tablets.
  • Sucralfate is also available in a 1g/10 ml suspension.

Dosing Information of Sucralfate for Dogs and Cats