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Ketorolac Ophthalmic Solution (Acular®) for Dogs and Cats

Ketorolac Ophthalmic Solution (Acular®) for Dogs and Cats

Overview of Ketorolac Ophthalmic Solution for Dogs and Cats

  • Ketorolac tromethamine, commonly known as Acular®, is a topical drug used to treat certain kinds of inflammation within the eye in dogs and cats.
  • Ketorolac inhibits the production of prostaglandins. Inhibiting this hormone helps decrease the inflammatory response in the eye.
  • Ketorolac belongs to a class of drugs called nonsteroidal anti-inflammatory drugs.
  • Ketorolac is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.
  • This drug is not approved for use in animals by the Food and Drug Administration (FDA), but it is prescribed legally by veterinarians as an extra-label.
  • Brand Names and Other Names of Ketorolac

  • This drug is registered for use in humans only.
  • Human formulations: Acular® 0.5% (Allergan)
  • Veterinary formulations: None
  • Uses of Ketorolac for Dogs and Cats

  • Ketorolac is used in the treatment of certain types of anterior uveitis and iritis.
  • It is particularly useful in the control of chronic uveitis where long-term usage of topical corticosteroids may produce undesirable side effects. Examples include chronic anterior uveitis in cats, lens-induced uveitis in dogs, and any chronic uveitis in animals with diabetes mellitus.
  • Ketorolac may also be used as a pre-operative and post-operative anti-inflammatory agent, especially to combat uveitis associated with eye surgery.
  • Ketorolac has been widely used for treating seasonal allergic conjunctivitis in people and may have similar benefits in cats and dogs.
  • Precautions and Side Effects

  • While generally safe and effective when prescribed by a veterinarian, ketorolac can cause side effects in some animals.
  • Ketorolac should not be used in animals with known hypersensitivity or allergy to the drug, or to any of the topical or systemic NSAIDs.
  • With any NSAID, there is the potential for increased bleeding due to their affect on platelet aggregation.
  • The drug should not be used in the presence of an eye hemorrhage or clotting abnormalities. It may potentially increase bleeding tendencies during eye surgery when used preoperatively.
  • Ketorolac delays wound healing and should be avoided if corneal ulceration is present. It should be used cautiously during the active wound-healing phase following eye surgery.
  • It should not be used in cases of glaucoma, and pressure within the eye should be monitored carefully after administration.
  • Ketorolac may interact with other medications. Consult your veterinarian to determine if other drugs your pet is taking could interact with ketorolac. Such drugs may include corticosteroids.
  • How Ketorolac Is Supplied

  • Ketorolac is available as a 0.5% solution in 3 ml, 5 ml and 10 ml bottles.
  • Dosing Information of Ketorolac for Dogs and Cats

  • Medication should never be administered without first consulting your veterinarian.
  • Ketorolac is usually administered 2 to 3 times daily for the treatment of active uveitis or conjunctivitis, and 1 to 2 times daily for the control of chronic uveitis.
  • As an adjunctive therapy to intraocular surgery, ketorolac may be administered 2 to 3 times daily over the two days prior to surgery, or for 2 to 3 doses just prior to surgery. It may then be continued for several days after surgery.
  • The duration of administration depends on the condition being treated, response to the medication, and the development of any adverse effects.
  • Ophthalmic Drugs

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    Ophthalmology & Ocular diseases

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